A third human carnitine/organic cation transporter ( OCTN3) as a candidate for the 5q31 Crohn’s disease locus ( IBD5)

Organic cation transporters function primarily in the elimination of cationic drugs in kidney, intestine, and liver [1–3]. The murine organic cation/carnitine ( Octn) transporter family, Octn1, Octn2, and Octn3 is clustered on mouse chromosome 11 (NCBI Accession No. NW_000039). The human OCTN1 and O...

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Veröffentlicht in:	Biochemical and biophysical research communications 2003-01, Vol.301 (1), p.98-101
Hauptverfasser:	Lamhonwah, Anne-Marie, Skaug, Jennifer, Scherer, Stephen W., Tein, Ingrid
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Transport - physiology Carnitine - metabolism Carnitine transporter Cells, Cultured Chromosomes, Human, Pair 5 - genetics Crohn Disease - genetics Crohn’s disease Fibroblasts - cytology Fibroblasts - metabolism Humans Mice Mice, Inbred C57BL OCTN3 gene Organic Cation Transport Proteins - genetics Organic Cation Transport Proteins - metabolism Organic cation transporter Peroxisomes Peroxisomes - metabolism Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Tumor Cells, Cultured
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