Liver‐Specific Gene Expression in Cultured Human Hematopoietic Stem Cells

Hematopoietic and hepatic stem cells share characteristic markers such as CD34, c‐kit, and Thy1. Based on the recent observations that hepatocytes may originate from bone marrow, we investigated the potential of CD34+ bone marrow cells to differentiate into hepatocytic cells in vitro. CD34+ and CD34...

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Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 2003-01, Vol.21 (1), p.98-104
Hauptverfasser:	Fiegel, Henning C., Lioznov, Michael V., Cortes‐Dericks, Lourdes, Lange, Claudia, Kluth, Dietrich, Fehse, Boris, Zander, Axel R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult bone marrow stem cells Albumins - biosynthesis Antigens, CD34 - biosynthesis Bone Marrow Bone Marrow Transplantation Cell Count Cell Differentiation - genetics Cells, Cultured Female Flow Cytometry Gene Expression Regulation - genetics Hematopoietic Stem Cells - chemistry Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - metabolism Hepatic stem cells Hepatocytes - chemistry Hepatocytes - cytology Hepatocytes - metabolism Humans Immunomagnetic Separation Ki-67 Antigen - biosynthesis Ki-67 Antigen - immunology Liver - chemistry Liver - metabolism Male Organ Specificity - genetics Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - biosynthesis Stem cell culture Stem Cells - chemistry Stem Cells - cytology Stem Cells - metabolism Transplantation, Homologous
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