Live now - pay by ageing: high performance mitochondrial activity in youth and its age-related side effects

Radical oxygen species are a byproduct of normal energy metabolism in mitochondria. The short-lived radicals cause damage to their immediate surrounding, i.e. the mitochondria. While most of this damage will be removed by normal mitochondrial turnover, damage to mitochondrial DNA (mtDNA) can persist...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Experimental physiology 2003-01, Vol.88 (1), p.167-174
Hauptverfasser:	Hofhaus, G., Berneburg, M., Wulfert, M., Gattermann, N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - genetics Aging - physiology Animals DNA Damage - genetics DNA Damage - physiology DNA, Mitochondrial - genetics DNA, Mitochondrial - physiology Energy Metabolism - physiology Humans Mitochondria - genetics Mitochondria - metabolism Mitochondria - physiology Reactive Oxygen Species - metabolism Special Review Series - Biogenesis and Physiological Adaptation of Mitochondria
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!