Specificity mapping of patients IgE response towards the tree pollen major allergens Aln g I, Bet v I and Cor a I
Summary The specificity pattern of IgE from non‐treated tree pollen allergic patients (n= 38) were evaluated by solid phase absorption of serum samples followed by CRIE on alder, birch and hazel CIE precipitation profiles. The majority of the serum samples seemed to contain IgE antibodies with the f...
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| Veröffentlicht in: | Clinical and experimental allergy 1992-03, Vol.22 (3), p.391-399 |
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| container_end_page | 399 |
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| container_title | Clinical and experimental allergy |
| container_volume | 22 |
| creator | IPSEN, H. WIHL, J.-Å. PETERSEN, B. NÜCHEL LØWENSTEIN, H. |
| description | Summary
The specificity pattern of IgE from non‐treated tree pollen allergic patients (n= 38) were evaluated by solid phase absorption of serum samples followed by CRIE on alder, birch and hazel CIE precipitation profiles. The majority of the serum samples seemed to contain IgE antibodies with the following characteristics: specific towards Bet v I alone and common between Aln g I, Bet v I and/or Cor a I, ‘II’. The IgE specificity profiles observed for 95% of the sera tested are compatible with birch pollen allergens being the only sensitizing allergens, indicating that the patients react to allergens from other tree pollens of the Fagales order due to IgE cross‐reaction with the major allergens of birch and alder and/or hazel pollens. |
| doi_str_mv | 10.1111/j.1365-2222.1992.tb03101.x |
| format | Article |
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The specificity pattern of IgE from non‐treated tree pollen allergic patients (n= 38) were evaluated by solid phase absorption of serum samples followed by CRIE on alder, birch and hazel CIE precipitation profiles. The majority of the serum samples seemed to contain IgE antibodies with the following characteristics: specific towards Bet v I alone and common between Aln g I, Bet v I and/or Cor a I, ‘II’. The IgE specificity profiles observed for 95% of the sera tested are compatible with birch pollen allergens being the only sensitizing allergens, indicating that the patients react to allergens from other tree pollens of the Fagales order due to IgE cross‐reaction with the major allergens of birch and alder and/or hazel pollens.</description><identifier>ISSN: 0954-7894</identifier><identifier>EISSN: 1365-2222</identifier><identifier>DOI: 10.1111/j.1365-2222.1992.tb03101.x</identifier><identifier>PMID: 1375127</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Allergens - immunology ; Allergic diseases ; Antibodies - analysis ; Antibodies - immunology ; Antibody Specificity ; Antigens, Plant ; Autoradiography ; Biological and medical sciences ; Cross Reactions - immunology ; Epitopes - analysis ; Humans ; Hypersensitivity - blood ; Hypersensitivity - immunology ; Immunoglobulin E - analysis ; Immunoglobulin E - immunology ; Immunopathology ; Medical sciences ; Plant Proteins - immunology ; Respiratory and ent allergic diseases</subject><ispartof>Clinical and experimental allergy, 1992-03, Vol.22 (3), p.391-399</ispartof><rights>1992 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4361-17c21d3f31ea7f7451b95548b761a21823fee9df8fbe4e5e0c1c025b31da9ac13</citedby><cites>FETCH-LOGICAL-c4361-17c21d3f31ea7f7451b95548b761a21823fee9df8fbe4e5e0c1c025b31da9ac13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1365-2222.1992.tb03101.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1365-2222.1992.tb03101.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=5270810$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1375127$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>IPSEN, H.</creatorcontrib><creatorcontrib>WIHL, J.-Å.</creatorcontrib><creatorcontrib>PETERSEN, B. NÜCHEL</creatorcontrib><creatorcontrib>LØWENSTEIN, H.</creatorcontrib><title>Specificity mapping of patients IgE response towards the tree pollen major allergens Aln g I, Bet v I and Cor a I</title><title>Clinical and experimental allergy</title><addtitle>Clin Exp Allergy</addtitle><description>Summary
The specificity pattern of IgE from non‐treated tree pollen allergic patients (n= 38) were evaluated by solid phase absorption of serum samples followed by CRIE on alder, birch and hazel CIE precipitation profiles. The majority of the serum samples seemed to contain IgE antibodies with the following characteristics: specific towards Bet v I alone and common between Aln g I, Bet v I and/or Cor a I, ‘II’. The IgE specificity profiles observed for 95% of the sera tested are compatible with birch pollen allergens being the only sensitizing allergens, indicating that the patients react to allergens from other tree pollens of the Fagales order due to IgE cross‐reaction with the major allergens of birch and alder and/or hazel pollens.</description><subject>Allergens - immunology</subject><subject>Allergic diseases</subject><subject>Antibodies - analysis</subject><subject>Antibodies - immunology</subject><subject>Antibody Specificity</subject><subject>Antigens, Plant</subject><subject>Autoradiography</subject><subject>Biological and medical sciences</subject><subject>Cross Reactions - immunology</subject><subject>Epitopes - analysis</subject><subject>Humans</subject><subject>Hypersensitivity - blood</subject><subject>Hypersensitivity - immunology</subject><subject>Immunoglobulin E - analysis</subject><subject>Immunoglobulin E - immunology</subject><subject>Immunopathology</subject><subject>Medical sciences</subject><subject>Plant Proteins - immunology</subject><subject>Respiratory and ent allergic diseases</subject><issn>0954-7894</issn><issn>1365-2222</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkEGP0zAQhSMEWsrCT0CyEOJEgieO45jDSiXqLpFWIARouVmOMy4uaZK1093235OoVTkzF4_0vjczflH0BmgCU33YJMByHqdTJSBlmow1ZUAh2T-JFmfpabSgkmexKGT2PHoRwoZSyrgsLqILYIJDKhbR_fcBjbPOuPFAtnoYXLcmvSWDHh12YyDVekU8hqHvApKxf9S-CWT8PfUekQx922I3GTe9J3rq_Rq7QJZtR9akek8-4UgeSEV015ByRkj1MnpmdRvw1em9jH5er36Un-PbrzdVubyNTcZyiEGYFBpmGaAWVmQcasl5VtQiB51CkTKLKBtb2Boz5EgNGJrymkGjpTbALqN3x7mD7-93GEa1dcFg2-oO-11QIpU5LxibwI9H0Pg-BI9WDd5ttT8ooGrOW23UHKqaQ1Vz3uqUt9pP5tenLbt6i80_6zHgSX970nUwurVed8aFM8ZTQQugE3Z1xB5di4f_OECVqyWT82_j4wAXRtyfB2j_R-ViukXdfblR8ld5R0F8U4z9BTPRqq0</recordid><startdate>199203</startdate><enddate>199203</enddate><creator>IPSEN, H.</creator><creator>WIHL, J.-Å.</creator><creator>PETERSEN, B. NÜCHEL</creator><creator>LØWENSTEIN, H.</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199203</creationdate><title>Specificity mapping of patients IgE response towards the tree pollen major allergens Aln g I, Bet v I and Cor a I</title><author>IPSEN, H. ; WIHL, J.-Å. ; PETERSEN, B. NÜCHEL ; LØWENSTEIN, H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4361-17c21d3f31ea7f7451b95548b761a21823fee9df8fbe4e5e0c1c025b31da9ac13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Allergens - immunology</topic><topic>Allergic diseases</topic><topic>Antibodies - analysis</topic><topic>Antibodies - immunology</topic><topic>Antibody Specificity</topic><topic>Antigens, Plant</topic><topic>Autoradiography</topic><topic>Biological and medical sciences</topic><topic>Cross Reactions - immunology</topic><topic>Epitopes - analysis</topic><topic>Humans</topic><topic>Hypersensitivity - blood</topic><topic>Hypersensitivity - immunology</topic><topic>Immunoglobulin E - analysis</topic><topic>Immunoglobulin E - immunology</topic><topic>Immunopathology</topic><topic>Medical sciences</topic><topic>Plant Proteins - immunology</topic><topic>Respiratory and ent allergic diseases</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>IPSEN, H.</creatorcontrib><creatorcontrib>WIHL, J.-Å.</creatorcontrib><creatorcontrib>PETERSEN, B. NÜCHEL</creatorcontrib><creatorcontrib>LØWENSTEIN, H.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical and experimental allergy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>IPSEN, H.</au><au>WIHL, J.-Å.</au><au>PETERSEN, B. NÜCHEL</au><au>LØWENSTEIN, H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Specificity mapping of patients IgE response towards the tree pollen major allergens Aln g I, Bet v I and Cor a I</atitle><jtitle>Clinical and experimental allergy</jtitle><addtitle>Clin Exp Allergy</addtitle><date>1992-03</date><risdate>1992</risdate><volume>22</volume><issue>3</issue><spage>391</spage><epage>399</epage><pages>391-399</pages><issn>0954-7894</issn><eissn>1365-2222</eissn><abstract>Summary
The specificity pattern of IgE from non‐treated tree pollen allergic patients (n= 38) were evaluated by solid phase absorption of serum samples followed by CRIE on alder, birch and hazel CIE precipitation profiles. The majority of the serum samples seemed to contain IgE antibodies with the following characteristics: specific towards Bet v I alone and common between Aln g I, Bet v I and/or Cor a I, ‘II’. The IgE specificity profiles observed for 95% of the sera tested are compatible with birch pollen allergens being the only sensitizing allergens, indicating that the patients react to allergens from other tree pollens of the Fagales order due to IgE cross‐reaction with the major allergens of birch and alder and/or hazel pollens.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>1375127</pmid><doi>10.1111/j.1365-2222.1992.tb03101.x</doi><tpages>9</tpages></addata></record> |
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| ispartof | Clinical and experimental allergy, 1992-03, Vol.22 (3), p.391-399 |
| issn | 0954-7894 1365-2222 |
| language | eng |
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| source | MEDLINE; Wiley Online Library All Journals |
| subjects | Allergens - immunology Allergic diseases Antibodies - analysis Antibodies - immunology Antibody Specificity Antigens, Plant Autoradiography Biological and medical sciences Cross Reactions - immunology Epitopes - analysis Humans Hypersensitivity - blood Hypersensitivity - immunology Immunoglobulin E - analysis Immunoglobulin E - immunology Immunopathology Medical sciences Plant Proteins - immunology Respiratory and ent allergic diseases |
| title | Specificity mapping of patients IgE response towards the tree pollen major allergens Aln g I, Bet v I and Cor a I |
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