Highly Regioselective Friedländer Annulations with Unmodified Ketones Employing Novel Amine Catalysts:  Syntheses of 2-Substituted Quinolines, 1,8-Naphthyridines, and Related Heterocycles

Catalysts were evaluated on the preparation of 2-substituted quinolines, 1,8-naphthyridines, and chromone derivatives from unmodified methyl ketones and o-aminoaromatic aldehydes. While oxide catalysts yielded the 2,3-dialkyl substituted products, cyclic secondary amines provided the 2-alkylsubstuti...

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Veröffentlicht in:	Journal of organic chemistry 2003-01, Vol.68 (2), p.467-477
Hauptverfasser:	Dormer, Peter G, Eng, Kan K, Farr, Roger N, Humphrey, Guy R, McWilliams, J. Christopher, Reider, P. J, Sager, Jess W, Volante, R. P
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings Organic chemistry Preparations and properties
Online-Zugang:	Volltext
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