Progesterone-modulated induction of apoptosis by interferon-tau in cultured epithelial cells of bovine endometrium

Interferon-tau (IFN-Ï) is produced by the trophoblast prior to implantation in ruminants. It is involved in maternal recognition of pregnancy, and is a pleiotropic molecule that can alter the synthesis of endometrial proteins and inhibit proliferation of some cells. We have observed that IFN-Ï red...

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Veröffentlicht in:	Biology of reproduction 2003-02, Vol.68 (2), p.673-679
Hauptverfasser:	Wang, B, Xiao, C, Goff, A.K
Format:	Artikel
Sprache:	eng
Schlagworte:	animal proteins Animals apoptosis Apoptosis - physiology Bax-alpha protein Biological and medical sciences Cattle Cells, Cultured cultured cells cycloheximide DNA DNA - metabolism DNA fragmentation endometrium Endometrium - cytology Endometrium - drug effects Endometrium - physiology epithelial cells Epithelial Cells - drug effects Epithelial Cells - physiology Female Fundamental and applied biological sciences. Psychology hormonal regulation Hormone metabolism and regulation Interferon Type I - pharmacology interferons Mammalian female genital system Pregnancy Proteins - pharmacology proapoptotic proteins progesterone Progesterone - pharmacology Progesterone - physiology protein content Proteins - metabolism Vertebrates: reproduction
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