Specific MR imaging of human lymphocytes by monoclonal antibody-guided dextran-magnetite particles

Human lymphocytes were labeled with biotinylated anti‐lymphocyte‐directed monoclonal antibodies, to which streptavidin and subsequently biotinylated dextran‐magnetite particles were coupled. This labeling resulted in a strong and selective negative contrast enhancement of lymphocyte suspensions at 2...

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Veröffentlicht in:	Magnetic resonance in medicine 1992-05, Vol.25 (1), p.148-157
Hauptverfasser:	Bulte, Jeff W. M., Hoekstra, Yke, Kamman, Richard L., Magin, Richard L., Webb, Andrew G., Briggs, Richard W., Gwan Go, K., Hulstaert, Caesar E., Miltenyi, Stefan, Hauw The, T., De Leij, Lou
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal Bacterial Proteins Contrast Media Dextrans Ferrosoferric Oxide Humans In Vitro Techniques Iron Lymphocytes - pathology Magnetic Resonance Imaging - methods Oxides Streptavidin
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