A surface energy analysis of mucoadhesion : contact angle measurements on polycarbophil and pig intestinal mucosa in physiologically relevant fluids

The possible role of surface energy thermodynamics in mucoadhesion was investigated with Polycarbophil and pig intestinal mucosa. In separate experiments, the surface energy parameters of the substrate (mucosa) and the adhesive (polymer film) were determined by contact angle measurements on captive...

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Veröffentlicht in:Pharmaceutical research 1992, Vol.9 (1), p.70-75
Hauptverfasser: LEHR, C.-M, BOUWSTRA, J. A, BODDE, H. E, JUNGINTER, H. E
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Sprache:eng
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