Prolonged endothelial-dependent and -independent arterial dysfunction induced in the rat by short-term feeding with a high-fat, high-sucrose diet

Obesity induced by long-term consumption of a fat-rich diet causes marked endothelial dysfunction. In this study we aimed to determine whether endothelial impairment is due to obesity or the diet per se. Wistar rats were fed either standard laboratory chow throughout (controls), or given a highly pa...

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