Lectin control of protein folding and sorting in the secretory pathway

Glycan moieties are essential for folding, sorting and targeting of glycoproteins through the secretory pathway to various cellular compartments. The molecular mechanisms that underlie these processes, however, are only now coming to light. Recent crystallographic and NMR studies of proteins located...

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Veröffentlicht in:	Trends in biochemical sciences (Amsterdam. Regular ed.) 2003, Vol.28 (1), p.49-57
Hauptverfasser:	Schrag, Joseph D, Procopio, Daniela O, Cygler, Miroslaw, Thomas, David Y, Bergeron, John J.M
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Calnexin - chemistry Calnexin - physiology Calreticulin - chemistry Endoplasmic Reticulum - metabolism Golgi Apparatus - metabolism Lectins - physiology Molecular Sequence Data Protein Conformation Protein Folding Protein Transport Sequence Homology, Amino Acid
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