Molecular evolution of the mammalian prion protein

Prion protein (PrP) sequences are until now available for only six of the 18 orders of placental mammals. A broader comparison of mammalian prions might help to understand the enigmatic functional and pathogenic properties of this protein. We therefore determined PrP coding sequences in 26 mammalian...

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Veröffentlicht in:	Molecular biology and evolution 2003-01, Vol.20 (1), p.111-121
Hauptverfasser:	van Rheede, Teun, Smolenaars, Marcel M W, Madsen, Ole, de Jong, Wilfried W
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amyloid - classification Amyloid - genetics Animals Base Sequence Evolution, Molecular Humans Molecular Sequence Data Phylogeny Prion Proteins Prions Protein Precursors - classification Protein Precursors - genetics Sequence Alignment
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