Treatment of Large Juvenile Nasopharyngeal Angiofibroma

The management of large juvenile nasopharyngeal angiofibromas with intracranial extension is controversial. We review our experience since 1980 with eighteen patients with juvenile nasopharyngeal angiofibroma. A diagnostic and treatment approach consisting of preoperative magnetic resonance imaging,...

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Veröffentlicht in:	Otolaryngology-head and neck surgery 1992-03, Vol.106 (3), p.278-282
Hauptverfasser:	Deschler, Daniel G., Kaplan, Michael J., Boles, Roger
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Child Combined Modality Therapy Embolization, Therapeutic Follow-Up Studies Histiocytoma, Benign Fibrous - surgery Histiocytoma, Benign Fibrous - therapy Humans Magnetic Resonance Imaging Male Middle Aged Nasopharyngeal Neoplasms - surgery Nasopharyngeal Neoplasms - therapy Neoplasm Recurrence, Local Postoperative Complications
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container_title	Otolaryngology-head and neck surgery
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creator	Deschler, Daniel G. Kaplan, Michael J. Boles, Roger
description	The management of large juvenile nasopharyngeal angiofibromas with intracranial extension is controversial. We review our experience since 1980 with eighteen patients with juvenile nasopharyngeal angiofibroma. A diagnostic and treatment approach consisting of preoperative magnetic resonance imaging, embolization of feeding branches from the external carotid artery, and attempted complete resection was used in seven patients with intracranial disease since 1987. Serial magnetic resonance images were used for followup. Intracranial disease that was persistent or recurrent and demonstrated subsequent growth was irradiated (35 to 45 cGy). Extracranial tumor recurrences were reexcised. We advocate this approach as a safe and effective alternative to primary irradiation and its sequelae.
doi_str_mv	10.1177/019459989210600315
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subjects	Adolescent Adult Child Combined Modality Therapy Embolization, Therapeutic Follow-Up Studies Histiocytoma, Benign Fibrous - surgery Histiocytoma, Benign Fibrous - therapy Humans Magnetic Resonance Imaging Male Middle Aged Nasopharyngeal Neoplasms - surgery Nasopharyngeal Neoplasms - therapy Neoplasm Recurrence, Local Postoperative Complications
title	Treatment of Large Juvenile Nasopharyngeal Angiofibroma
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