Squamous Cell Carcinoma in Older Patients without Risk Factors
Ten patients over sixty years of age with no history of tobacco or alcohol use were treated for squamous cell carcinoma of the upper aerodigestive tract between 1979 and 1991. Nine of these ten patients were women with lesions confined to the oral cavity and oropharynx. Modes of treatment included s...
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| Veröffentlicht in: | Otolaryngology-head and neck surgery 1992-03, Vol.106 (3), p.275-277 |
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| container_title | Otolaryngology-head and neck surgery |
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| creator | Constantinides, Minas S. Rothstein, Stephen G. Persky, Mark S. |
| description | Ten patients over sixty years of age with no history of tobacco or alcohol use were treated for squamous cell carcinoma of the upper aerodigestive tract between 1979 and 1991. Nine of these ten patients were women with lesions confined to the oral cavity and oropharynx. Modes of treatment included surgery, radiation, or a combination of surgery and radiation. Followup from 1 to 10 years revealed two deaths from local and distant spread, and eight patients with no evidence of disease. Recurrences after treatment were aggressive and occurred within the same region as the primary lesion. Although most patients with upper aerodigestive squamous cell carcinoma are men with alcohol and/or tobacco exposure, this study demonstrates findings consistent with field cancerization in a group of older women with no risk factors. |
| doi_str_mv | 10.1177/019459989210600314 |
| format | Article |
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Nine of these ten patients were women with lesions confined to the oral cavity and oropharynx. Modes of treatment included surgery, radiation, or a combination of surgery and radiation. Followup from 1 to 10 years revealed two deaths from local and distant spread, and eight patients with no evidence of disease. Recurrences after treatment were aggressive and occurred within the same region as the primary lesion. Although most patients with upper aerodigestive squamous cell carcinoma are men with alcohol and/or tobacco exposure, this study demonstrates findings consistent with field cancerization in a group of older women with no risk factors.</description><identifier>ISSN: 0194-5998</identifier><identifier>EISSN: 1097-6817</identifier><identifier>DOI: 10.1177/019459989210600314</identifier><identifier>PMID: 1589220</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Aged ; Aged, 80 and over ; Carcinoma, Squamous Cell - etiology ; Carcinoma, Squamous Cell - mortality ; Carcinoma, Squamous Cell - therapy ; Combined Modality Therapy ; Female ; Follow-Up Studies ; Humans ; Laryngeal Neoplasms - etiology ; Laryngeal Neoplasms - mortality ; Laryngeal Neoplasms - therapy ; Male ; Middle Aged ; Mouth Neoplasms - etiology ; Mouth Neoplasms - mortality ; Mouth Neoplasms - therapy ; Neoplasm Recurrence, Local ; Oropharyngeal Neoplasms - etiology ; Oropharyngeal Neoplasms - mortality ; Oropharyngeal Neoplasms - therapy ; Retrospective Studies ; Risk Factors</subject><ispartof>Otolaryngology-head and neck surgery, 1992-03, Vol.106 (3), p.275-277</ispartof><rights>1992 Official journal of the American Academy of Otolaryngology–Head and Neck Surgery Foundation</rights><rights>1992 American Association of Otolaryngology‐Head and Neck Surgery Foundation (AAO‐HNSF)</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3892-e19bcfbea8418f61f5190d895b5348a4168967996f0c60b1e305f305195599993</citedby><cites>FETCH-LOGICAL-c3892-e19bcfbea8418f61f5190d895b5348a4168967996f0c60b1e305f305195599993</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1177%2F019459989210600314$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1177%2F019459989210600314$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1589220$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Constantinides, Minas S.</creatorcontrib><creatorcontrib>Rothstein, Stephen G.</creatorcontrib><creatorcontrib>Persky, Mark S.</creatorcontrib><title>Squamous Cell Carcinoma in Older Patients without Risk Factors</title><title>Otolaryngology-head and neck surgery</title><addtitle>Otolaryngol Head Neck Surg</addtitle><description>Ten patients over sixty years of age with no history of tobacco or alcohol use were treated for squamous cell carcinoma of the upper aerodigestive tract between 1979 and 1991. Nine of these ten patients were women with lesions confined to the oral cavity and oropharynx. Modes of treatment included surgery, radiation, or a combination of surgery and radiation. Followup from 1 to 10 years revealed two deaths from local and distant spread, and eight patients with no evidence of disease. Recurrences after treatment were aggressive and occurred within the same region as the primary lesion. Although most patients with upper aerodigestive squamous cell carcinoma are men with alcohol and/or tobacco exposure, this study demonstrates findings consistent with field cancerization in a group of older women with no risk factors.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Carcinoma, Squamous Cell - etiology</subject><subject>Carcinoma, Squamous Cell - mortality</subject><subject>Carcinoma, Squamous Cell - therapy</subject><subject>Combined Modality Therapy</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Laryngeal Neoplasms - etiology</subject><subject>Laryngeal Neoplasms - mortality</subject><subject>Laryngeal Neoplasms - therapy</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mouth Neoplasms - etiology</subject><subject>Mouth Neoplasms - mortality</subject><subject>Mouth Neoplasms - therapy</subject><subject>Neoplasm Recurrence, Local</subject><subject>Oropharyngeal Neoplasms - etiology</subject><subject>Oropharyngeal Neoplasms - mortality</subject><subject>Oropharyngeal Neoplasms - therapy</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><issn>0194-5998</issn><issn>1097-6817</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkN1LwzAUxYMoc07_AUHIk291uW2TND4IWpwThhM_nkPapZrZjy1pGfvvzejAB0F8uNyHe37nHg5C50CuADgfExAxFSIRIRBGSATxARoCETxgCfBDNNwJgp3iGJ04tySEMMb5AA2AeigkQ3Tzuu5U1XQOp7oscapsbuqmUtjUeF4utMXPqjW6bh3emPaz6Vr8YtwXnqi8baw7RUeFKp0-2-8Rep_cv6XTYDZ_eExvZ0Ee-UeBBpHlRaZVEkNSMCgoCLJIBM1oFCcqBpYIxoVgBckZyUBHhBZ-QFCfXohohC5735Vt1p12rayMy31iVWsfXvJQ0JDGO2HYC3PbOGd1IVfWVMpuJRC5K03-Ls1DF3v3Lqv04gfpW_L36_6-MaXe_sNRzqdPdxMSxRB6eNzDTn1ouWw6W_um_orzDaUugmw</recordid><startdate>199203</startdate><enddate>199203</enddate><creator>Constantinides, Minas S.</creator><creator>Rothstein, Stephen G.</creator><creator>Persky, Mark S.</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>8BM</scope></search><sort><creationdate>199203</creationdate><title>Squamous Cell Carcinoma in Older Patients without Risk Factors</title><author>Constantinides, Minas S. ; Rothstein, Stephen G. ; Persky, Mark S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3892-e19bcfbea8418f61f5190d895b5348a4168967996f0c60b1e305f305195599993</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Carcinoma, Squamous Cell - etiology</topic><topic>Carcinoma, Squamous Cell - mortality</topic><topic>Carcinoma, Squamous Cell - therapy</topic><topic>Combined Modality Therapy</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Laryngeal Neoplasms - etiology</topic><topic>Laryngeal Neoplasms - mortality</topic><topic>Laryngeal Neoplasms - therapy</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mouth Neoplasms - etiology</topic><topic>Mouth Neoplasms - mortality</topic><topic>Mouth Neoplasms - therapy</topic><topic>Neoplasm Recurrence, Local</topic><topic>Oropharyngeal Neoplasms - etiology</topic><topic>Oropharyngeal Neoplasms - mortality</topic><topic>Oropharyngeal Neoplasms - therapy</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Constantinides, Minas S.</creatorcontrib><creatorcontrib>Rothstein, Stephen G.</creatorcontrib><creatorcontrib>Persky, Mark S.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>ComDisDome</collection><jtitle>Otolaryngology-head and neck surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Constantinides, Minas S.</au><au>Rothstein, Stephen G.</au><au>Persky, Mark S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Squamous Cell Carcinoma in Older Patients without Risk Factors</atitle><jtitle>Otolaryngology-head and neck surgery</jtitle><addtitle>Otolaryngol Head Neck Surg</addtitle><date>1992-03</date><risdate>1992</risdate><volume>106</volume><issue>3</issue><spage>275</spage><epage>277</epage><pages>275-277</pages><issn>0194-5998</issn><eissn>1097-6817</eissn><abstract>Ten patients over sixty years of age with no history of tobacco or alcohol use were treated for squamous cell carcinoma of the upper aerodigestive tract between 1979 and 1991. Nine of these ten patients were women with lesions confined to the oral cavity and oropharynx. Modes of treatment included surgery, radiation, or a combination of surgery and radiation. Followup from 1 to 10 years revealed two deaths from local and distant spread, and eight patients with no evidence of disease. Recurrences after treatment were aggressive and occurred within the same region as the primary lesion. Although most patients with upper aerodigestive squamous cell carcinoma are men with alcohol and/or tobacco exposure, this study demonstrates findings consistent with field cancerization in a group of older women with no risk factors.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>1589220</pmid><doi>10.1177/019459989210600314</doi><tpages>3</tpages></addata></record> |
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| ispartof | Otolaryngology-head and neck surgery, 1992-03, Vol.106 (3), p.275-277 |
| issn | 0194-5998 1097-6817 |
| language | eng |
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| source | Wiley Online Library Journals【Remote access available】; MEDLINE |
| subjects | Aged Aged, 80 and over Carcinoma, Squamous Cell - etiology Carcinoma, Squamous Cell - mortality Carcinoma, Squamous Cell - therapy Combined Modality Therapy Female Follow-Up Studies Humans Laryngeal Neoplasms - etiology Laryngeal Neoplasms - mortality Laryngeal Neoplasms - therapy Male Middle Aged Mouth Neoplasms - etiology Mouth Neoplasms - mortality Mouth Neoplasms - therapy Neoplasm Recurrence, Local Oropharyngeal Neoplasms - etiology Oropharyngeal Neoplasms - mortality Oropharyngeal Neoplasms - therapy Retrospective Studies Risk Factors |
| title | Squamous Cell Carcinoma in Older Patients without Risk Factors |
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