Intestinal IgA synthesis: regulation of front-line body defences

Key Points Intestinal immunoglobulin A (IgA) + plasma cells are derived from conventional B2 cells located in the Peyer's patches or isolated lymphoid follicles of the gut, and from B1 cells, which reside in the body cavities, in particular the peritoneal cavity. CCL25 is produced by the small...

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Veröffentlicht in:	Nature reviews. Immunology 2003-01, Vol.3 (1), p.63-72
Hauptverfasser:	Fagarasan, Sidonia, Honjo, Tasuku
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens Biomedical and Life Sciences Biomedicine Dendritic cells Flora Follicles Homeostasis Homeostasis - immunology Humans Immune system Immunity, Mucosal - immunology Immunoglobulin A - biosynthesis Immunoglobulin A - genetics Immunoglobulin A - immunology Immunoglobulin Class Switching - genetics Immunoglobulins Immunology Intestinal Mucosa - immunology Intestinal Mucosa - metabolism Plasma review-article
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