Subacute sclerosing panencephalitis is typically characterized by alterations in the fusion protein cytoplasmic domain of the persisting measles virus

Our recent extensive analysis of three cases of subacute sclerosing panencephalitis (SSPE) revealed intriguing genetic defects in the persisting measles virus (MV): the fusion (F) genes encoded truncated cytoplasmic F protein domains (Cattaneo et al., Virology 173, 415–425, 1989). Now this MV genomi...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 1992-06, Vol.188 (2), p.910-915
Hauptverfasser:	Schmid, Anita, Spielhofer, Pius, Cattaneo, Roberto, Baczko, Knut, Ter Meulen, Volker, Billeter, Martin A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Base Sequence Biological and medical sciences Cloning, Molecular Cytoplasm Human viral diseases Humans Infectious diseases measles virus Measles virus - genetics Medical sciences Molecular Sequence Data Oligodeoxyribonucleotides - chemistry Sequence Alignment Subacute Sclerosing Panencephalitis - microbiology Viral diseases Viral diseases of the nervous system Viral Fusion Proteins - genetics Viral Fusion Proteins - ultrastructure
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