Regulation of Complement Functional Efficiency by Histidine-Rich Glycoprotein

The modulation of complement functional efficiency by serum histidine-rich glycoprotein (HRG) was investigated. Addition of exogenous HRG to prewarmed diluted serum, followed immediately by sensitized sheep erythrocytes (EA), resulted in enhanced hemolysis. However, when HRG was incubated with dilut...

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Veröffentlicht in:	Blood 1992-06, Vol.79 (11), p.2973-2980
Hauptverfasser:	Chang, Nan-Shan, Leu, Richard W., Rummage, John A., Anderson, Jacqueline K., E. Mole, I John
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Complement Complement C8 - antagonists & inhibitors Complement C8 - immunology Complement C8 - metabolism Complement C9 - chemistry Complement C9 - metabolism Complement Factor B - metabolism Complement Factor D - antagonists & inhibitors Complement Factor D - metabolism Complement Pathway, Alternative - drug effects Complement System Proteins - immunology Elapid Venoms - metabolism Erythrocytes - immunology Fundamental and applied biological sciences. Psychology Fundamental immunology Glycoproteins - metabolism Glycoproteins - pharmacology Hemolysis Hot Temperature Humans Macromolecular Substances Molecular immunology Proteins - metabolism Proteins - pharmacology Rabbits Sheep Time Factors Vitronectin
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