Mechanisms of pain-induced local cerebral blood flow changes in the rat sensory cortex and thalamus

It is a well-known phenomenon that cerebral blood flow is coupled to neural activation induced by non-noxious somatosensory stimulation. However, basic questions related to pain-induced cerebral blood flow changes remain unanswered. In the present study, the sciatic nerve of anesthetized rats was su...

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Veröffentlicht in:	Brain research 2003-01, Vol.960 (1), p.219-227
Hauptverfasser:	Erdo&#x030B, s, Benedek, Lacza, Zsombor, Tóth, Ida E., Szelke, Emese, Mersich, Tamás, Komjáti, Katalin, Palkovits, Miklós, Sándor, Péter
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ATP dependent potassium channel ATP-Binding Cassette Transporters Biological and medical sciences Blood Gas Analysis Blood Pressure - drug effects Blood Pressure - physiology Cerebrovascular circulation Cerebrovascular Circulation - drug effects Cerebrovascular Circulation - physiology Endorphins - physiology Enzyme Inhibitors - pharmacology Fundamental and applied biological sciences. Psychology Genes, fos - genetics Immunohistochemistry KATP Channels Male Naloxone - pharmacology Narcotic Antagonists - pharmacology Nitric oxide Nitric Oxide - physiology Nitric Oxide Synthase - antagonists & inhibitors Nitric Oxide Synthase Type I Noxious somatosensory stimulation Pain - physiopathology Physical Stimulation Potassium Channel Blockers - pharmacology Potassium Channels - physiology Potassium Channels, Inwardly Rectifying Prostaglandin-Endoperoxide Synthases - physiology Rats Rats, Wistar Receptors, Adrenergic, alpha - physiology Receptors, Adrenergic, beta - physiology Sciatic Nerve - physiology Somatosensory Cortex - blood supply Somatosensory Cortex - physiopathology Somesthesis and somesthetic pathways (proprioception, exteroception, nociception) interoception electrolocation. Sensory receptors Stereotaxic Techniques Thalamus - blood supply Thalamus - physiopathology Vertebrates: nervous system and sense organs β-Receptor
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