In vitro assessment of the postantibiotic effect of lomefloxacin against gram-positive and gram-negative pathogens

We evaluated the postantibiotic effect (PAE) of lomefloxacin, a new difluorinated quinolone, on multiply drug-resistant gram-positive and gram-negative clinical pathogens. Lomefloxacin induced a PAE of about 2 hours in gram-negative and gram-positive bacteria exposed for 1 hour to concentrations cor...

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Veröffentlicht in:	The American journal of medicine 1992-04, Vol.92 (4), p.S45-S47
Hauptverfasser:	Debbia, Eugenio A., Pesce, Adelaide, Schito, Gian Carlo
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Infective Agents - pharmacology Ciprofloxacin - pharmacology Drug Evaluation, Preclinical Drug Resistance, Microbial Drug therapy Fluoroquinolones Gram-Negative Bacteria - drug effects Gram-Positive Bacteria - drug effects Medical research Microbial Sensitivity Tests Ofloxacin - pharmacology Pathology Quinolones - pharmacology Time Factors
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