Evaluation of a Genetically Modified Reassortant H5N1 Influenza A Virus Vaccine Candidate Generated by Plasmid-Based Reverse Genetics

Avian influenza A H5N1 viruses similar to those that infected humans in Hong Kong in 1997 continue to circulate in waterfowl and have reemerged in poultry in the region, raising concerns that these viruses could reappear in humans. The currently licensed trivalent inactivated influenza vaccines cont...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 2003-01, Vol.305 (1), p.192-200
Hauptverfasser:	Subbarao, Kanta, Chen, Hualan, Swayne, David, Mingay, Louise, Fodor, Ervin, Brownlee, George, Xu, Xiyan, Lu, Xiuhua, Katz, Jacqueline, Cox, Nancy, Matsuoka, Yumiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chickens Female Ferrets H5N1 vaccine Influenza A virus - genetics Influenza A virus - immunology Influenza A virus - pathogenicity Influenza A Virus, H5N1 Subtype Influenza Vaccines - immunology Mice Mice, Inbred BALB C pandemic influenza Plasmids Reassortant Viruses - immunology reverse genetics Transfection vaccines Vaccines, Attenuated - immunology Virus Replication
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