Functional interaction of megalin with the megalinbinding protein (MegBP), a novel tetratrico peptide repeat-containing adaptor molecule

Megalin is a member of the LDL receptor gene family that plays an important role in forebrain development and in cellular vitamin D metabolism through endocytic uptake of vitamin D metabolites. Similar to other receptors in this gene family, megalin is believed to functionally interact with intracel...

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Veröffentlicht in:	Journal of cell science 2003-02, Vol.116 (Pt 3), p.453-461
Hauptverfasser:	Petersen, Helle Heibroch, Hilpert, Jan, Militz, Daniel, Zandler, Valerie, Jacobsen, Christian, Roebroek, Anton J M, Willnow, Thomas E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing Adaptor Proteins, Vesicular Transport - genetics Adaptor Proteins, Vesicular Transport - isolation & purification Amino Acid Sequence - genetics Animals Base Sequence - genetics Binding Sites - physiology Carrier Proteins - genetics Carrier Proteins - isolation & purification Carrier Proteins - metabolism Cell Line Cell Membrane - metabolism DNA, Complementary - analysis DNA, Complementary - genetics Endocytosis - physiology Eukaryotic Cells - metabolism Genes, Regulator - physiology Humans Ligands Low Density Lipoprotein Receptor-Related Protein-2 - genetics Low Density Lipoprotein Receptor-Related Protein-2 - isolation & purification Low Density Lipoprotein Receptor-Related Protein-2 - metabolism Mice Molecular Sequence Data Nuclear Matrix-Associated Proteins - genetics Nuclear Matrix-Associated Proteins - isolation & purification Peptides - genetics Peptides - metabolism Protein Binding - physiology Protein Structure, Tertiary - physiology
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