Determinants of substrate affinity for the oligopeptide/H+ symporter in the renal brush border membrane

We and others have shown previously the existence of high and low affinity systems for oligopeptide transport in kidney brush border membrane vesicles (BBMV). In the present study we investigated the relationship between the structure of substrates and their affinity for interaction with the high-af...

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Veröffentlicht in:	The Journal of biological chemistry 1992-05, Vol.267 (14), p.9565-9573
Hauptverfasser:	DANIEL, H, MORSE, E. L, ADIBI, S. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Binding, Competitive Biological and medical sciences Carrier Proteins - metabolism Cell physiology Dipeptides - metabolism Fundamental and applied biological sciences. Psychology Kidney - metabolism Kinetics Male Membrane and intracellular transports Microvilli - metabolism Molecular and cellular biology Molecular Sequence Data Oligopeptides - metabolism Rats Rats, Inbred Strains Stereoisomerism Substrate Specificity
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