Alteration of Contractile Function and Excitation-Contraction Coupling in Dilated Cardiomyopathy

Myocardial failure in dilated cardiomyopathy may result from subcellular alterations in contractile protein function, excitation-contraction coupling processes, or recovery metabolism. We used isometric force and heat measurements to quantitatively investigate these subcellular systems in intact lef...

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Veröffentlicht in:	Circulation research 1992-06, Vol.70 (6), p.1225-1232
Hauptverfasser:	Hasenfuss, Gerd, Mulieri, Louis A, Leavitt, Bruce J, Allen, Paul D, Haeberle, Joe R, Alpert, Norman R
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Calcium - metabolism Cardiomyopathy, Dilated - metabolism Cardiomyopathy, Dilated - physiopathology Contractile Proteins - physiology Female Fundamental and applied biological sciences. Psychology Heart Heart - physiopathology Humans In Vitro Techniques Male Middle Aged Myocardial Contraction Myocardium - metabolism Vertebrates: cardiovascular system
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