Clinical significance of coagulase-negative staphylococci isolated from neonates

Clinical significance of coagulase-negative staphylococci isolated from neonates

To evaluate the clinical significance of coagulase-negative staphylococci (CNS) isolated from newborns' infections at Neonatal Unit of Hospital das Clínicas da Faculdade de Medicina de Botucatu. The CNS strains isolated were identified and classified as clinically significant and contaminant, b...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Jornal de pediatria 2002-07, Vol.78 (4), p.279-88
Hauptverfasser: Cunha, Maria de Lourdes R S, Lopes, Carlos A M, Rugolo, Lígia M S S, Chalita, Liciana V A S
Format: Artikel
Sprache:por
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 88
container_issue 4
container_start_page 279
container_title Jornal de pediatria
container_volume 78
creator Cunha, Maria de Lourdes R S
Lopes, Carlos A M
Rugolo, Lígia M S S
Chalita, Liciana V A S
description To evaluate the clinical significance of coagulase-negative staphylococci (CNS) isolated from newborns' infections at Neonatal Unit of Hospital das Clínicas da Faculdade de Medicina de Botucatu. The CNS strains isolated were identified and classified as clinically significant and contaminant, based on a series of clinical and laboratory data obtained from patients who stayed in the Neonatal Unit. The following data were analyzed: risk factors for infections, clinical evolution, abnormal blood cell counts and/or C-reactive protein and antibiotic therapy. Among the 117 CNS strains isolated, 60 (51.3%) were classified as significant and 57 (48.7%) as contaminant. Among the 54 infants infected by CNS, 43 (79.6%) presented very low birthweight (
doi_str_mv 10.2223/JPED.861
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_72923334</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>72923334</sourcerecordid><originalsourceid>FETCH-LOGICAL-c1268-c237aed2d23cb98fb1097f9653890445b95a8468c901409234b569818ce32ed53</originalsourceid><addsrcrecordid>eNpFkE1LAzEURbNQbK2Cv0BmJW6m5nuSpdT6RcEudB0ymaRGMpM6mSn035vSgqv3Hpx3uRwAbhCcY4zJw_t6-TQXHJ2BKYQYlRVj1QRcpvQDIeOSowswQZTTqmJiCtaL4DtvdCiS33Te5bUztoiuMFFvxqCTLTu70YPf2SINevu9D9FEY3zhUwx6sE3h-tgWnY1dvtIVOHc6JHt9mjPw9bz8XLyWq4-Xt8XjqjQIc1EaTCptG9xgYmopXI2grJzkjAgJKWW1ZFpQLoyEiEKJCa1zeYGEsQTbhpEZuDvmbvv4O9o0qNYnY0PQucmYVIXzEyE0g_dH0PQxpd46te19q_u9QlAdjKmDMZWNZfT2lDnWrW3-wZMu8gehBGfI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>72923334</pqid></control><display><type>article</type><title>Clinical significance of coagulase-negative staphylococci isolated from neonates</title><source>EZB-FREE-00999 freely available EZB journals</source><source>Alma/SFX Local Collection</source><creator>Cunha, Maria de Lourdes R S ; Lopes, Carlos A M ; Rugolo, Lígia M S S ; Chalita, Liciana V A S</creator><creatorcontrib>Cunha, Maria de Lourdes R S ; Lopes, Carlos A M ; Rugolo, Lígia M S S ; Chalita, Liciana V A S</creatorcontrib><description>To evaluate the clinical significance of coagulase-negative staphylococci (CNS) isolated from newborns' infections at Neonatal Unit of Hospital das Clínicas da Faculdade de Medicina de Botucatu. The CNS strains isolated were identified and classified as clinically significant and contaminant, based on a series of clinical and laboratory data obtained from patients who stayed in the Neonatal Unit. The following data were analyzed: risk factors for infections, clinical evolution, abnormal blood cell counts and/or C-reactive protein and antibiotic therapy. Among the 117 CNS strains isolated, 60 (51.3%) were classified as significant and 57 (48.7%) as contaminant. Among the 54 infants infected by CNS, 43 (79.6%) presented very low birthweight (&lt;1,500 g). Most of the infants infected by CNS were submitted to two or more invasive procedures (77.8%), including use of catheter (88.9%), parenteral nutrition (64.8%) and mechanical ventilation (61.1%). Staphylococcus epidermidis was the most frequently isolated species (77.8%) and more often associated with infection (86.7%) than with contamination (68.4%). Other species of CNS, including two strains of S. haemolyticus, three strains of S. lugdunensis, one strain of S. simulans, one strain of S. warneri and one strain of S. xylosus were also isolated from infants with clinical evidence of pneumonia, necrotizing enterocolitis and sepsis. Most newborns infected by CNS presented important risk factors for infection onset, including birthweight &lt;1,500 g, foreign body presence and previous use of antibiotics. The identification of CNS species constitutes a useful marker of infection, since S. epidermidis was the species more frequently associated with infection.</description><identifier>ISSN: 0021-7557</identifier><identifier>DOI: 10.2223/JPED.861</identifier><identifier>PMID: 14647758</identifier><language>por</language><publisher>Brazil</publisher><ispartof>Jornal de pediatria, 2002-07, Vol.78 (4), p.279-88</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c1268-c237aed2d23cb98fb1097f9653890445b95a8468c901409234b569818ce32ed53</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14647758$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cunha, Maria de Lourdes R S</creatorcontrib><creatorcontrib>Lopes, Carlos A M</creatorcontrib><creatorcontrib>Rugolo, Lígia M S S</creatorcontrib><creatorcontrib>Chalita, Liciana V A S</creatorcontrib><title>Clinical significance of coagulase-negative staphylococci isolated from neonates</title><title>Jornal de pediatria</title><addtitle>J Pediatr (Rio J)</addtitle><description>To evaluate the clinical significance of coagulase-negative staphylococci (CNS) isolated from newborns' infections at Neonatal Unit of Hospital das Clínicas da Faculdade de Medicina de Botucatu. The CNS strains isolated were identified and classified as clinically significant and contaminant, based on a series of clinical and laboratory data obtained from patients who stayed in the Neonatal Unit. The following data were analyzed: risk factors for infections, clinical evolution, abnormal blood cell counts and/or C-reactive protein and antibiotic therapy. Among the 117 CNS strains isolated, 60 (51.3%) were classified as significant and 57 (48.7%) as contaminant. Among the 54 infants infected by CNS, 43 (79.6%) presented very low birthweight (&lt;1,500 g). Most of the infants infected by CNS were submitted to two or more invasive procedures (77.8%), including use of catheter (88.9%), parenteral nutrition (64.8%) and mechanical ventilation (61.1%). Staphylococcus epidermidis was the most frequently isolated species (77.8%) and more often associated with infection (86.7%) than with contamination (68.4%). Other species of CNS, including two strains of S. haemolyticus, three strains of S. lugdunensis, one strain of S. simulans, one strain of S. warneri and one strain of S. xylosus were also isolated from infants with clinical evidence of pneumonia, necrotizing enterocolitis and sepsis. Most newborns infected by CNS presented important risk factors for infection onset, including birthweight &lt;1,500 g, foreign body presence and previous use of antibiotics. The identification of CNS species constitutes a useful marker of infection, since S. epidermidis was the species more frequently associated with infection.</description><issn>0021-7557</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><recordid>eNpFkE1LAzEURbNQbK2Cv0BmJW6m5nuSpdT6RcEudB0ymaRGMpM6mSn035vSgqv3Hpx3uRwAbhCcY4zJw_t6-TQXHJ2BKYQYlRVj1QRcpvQDIeOSowswQZTTqmJiCtaL4DtvdCiS33Te5bUztoiuMFFvxqCTLTu70YPf2SINevu9D9FEY3zhUwx6sE3h-tgWnY1dvtIVOHc6JHt9mjPw9bz8XLyWq4-Xt8XjqjQIc1EaTCptG9xgYmopXI2grJzkjAgJKWW1ZFpQLoyEiEKJCa1zeYGEsQTbhpEZuDvmbvv4O9o0qNYnY0PQucmYVIXzEyE0g_dH0PQxpd46te19q_u9QlAdjKmDMZWNZfT2lDnWrW3-wZMu8gehBGfI</recordid><startdate>200207</startdate><enddate>200207</enddate><creator>Cunha, Maria de Lourdes R S</creator><creator>Lopes, Carlos A M</creator><creator>Rugolo, Lígia M S S</creator><creator>Chalita, Liciana V A S</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200207</creationdate><title>Clinical significance of coagulase-negative staphylococci isolated from neonates</title><author>Cunha, Maria de Lourdes R S ; Lopes, Carlos A M ; Rugolo, Lígia M S S ; Chalita, Liciana V A S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1268-c237aed2d23cb98fb1097f9653890445b95a8468c901409234b569818ce32ed53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>por</language><creationdate>2002</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cunha, Maria de Lourdes R S</creatorcontrib><creatorcontrib>Lopes, Carlos A M</creatorcontrib><creatorcontrib>Rugolo, Lígia M S S</creatorcontrib><creatorcontrib>Chalita, Liciana V A S</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Jornal de pediatria</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cunha, Maria de Lourdes R S</au><au>Lopes, Carlos A M</au><au>Rugolo, Lígia M S S</au><au>Chalita, Liciana V A S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical significance of coagulase-negative staphylococci isolated from neonates</atitle><jtitle>Jornal de pediatria</jtitle><addtitle>J Pediatr (Rio J)</addtitle><date>2002-07</date><risdate>2002</risdate><volume>78</volume><issue>4</issue><spage>279</spage><epage>88</epage><pages>279-88</pages><issn>0021-7557</issn><abstract>To evaluate the clinical significance of coagulase-negative staphylococci (CNS) isolated from newborns' infections at Neonatal Unit of Hospital das Clínicas da Faculdade de Medicina de Botucatu. The CNS strains isolated were identified and classified as clinically significant and contaminant, based on a series of clinical and laboratory data obtained from patients who stayed in the Neonatal Unit. The following data were analyzed: risk factors for infections, clinical evolution, abnormal blood cell counts and/or C-reactive protein and antibiotic therapy. Among the 117 CNS strains isolated, 60 (51.3%) were classified as significant and 57 (48.7%) as contaminant. Among the 54 infants infected by CNS, 43 (79.6%) presented very low birthweight (&lt;1,500 g). Most of the infants infected by CNS were submitted to two or more invasive procedures (77.8%), including use of catheter (88.9%), parenteral nutrition (64.8%) and mechanical ventilation (61.1%). Staphylococcus epidermidis was the most frequently isolated species (77.8%) and more often associated with infection (86.7%) than with contamination (68.4%). Other species of CNS, including two strains of S. haemolyticus, three strains of S. lugdunensis, one strain of S. simulans, one strain of S. warneri and one strain of S. xylosus were also isolated from infants with clinical evidence of pneumonia, necrotizing enterocolitis and sepsis. Most newborns infected by CNS presented important risk factors for infection onset, including birthweight &lt;1,500 g, foreign body presence and previous use of antibiotics. The identification of CNS species constitutes a useful marker of infection, since S. epidermidis was the species more frequently associated with infection.</abstract><cop>Brazil</cop><pmid>14647758</pmid><doi>10.2223/JPED.861</doi><tpages>-190</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0021-7557
ispartof Jornal de pediatria, 2002-07, Vol.78 (4), p.279-88
issn 0021-7557
language por
recordid cdi_proquest_miscellaneous_72923334
source EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection
title Clinical significance of coagulase-negative staphylococci isolated from neonates
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T18%3A07%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Clinical%20significance%20of%20coagulase-negative%20staphylococci%20isolated%20from%20neonates&rft.jtitle=Jornal%20de%20pediatria&rft.au=Cunha,%20Maria%20de%20Lourdes%20R%20S&rft.date=2002-07&rft.volume=78&rft.issue=4&rft.spage=279&rft.epage=88&rft.pages=279-88&rft.issn=0021-7557&rft_id=info:doi/10.2223/JPED.861&rft_dat=%3Cproquest_cross%3E72923334%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=72923334&rft_id=info:pmid/14647758&rfr_iscdi=true