Amelioration of antigen‐induced arthritis in rabbits treated with monoclonal antibodies to leukocyte adhesion molecules

Objective. To examine the effects of treatment of antigen‐induced arthritis in rabbits with a monoclonal antibody against CD18, the common β chain of the leukocyte adhesion molecules. Intraarticular injection of antigen into primed rabbits elicits an acute inflammatory response followed by chronic a...

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Veröffentlicht in:	Arthritis and rheumatism 1992-05, Vol.35 (5), p.541-549
Hauptverfasser:	Jasin, Hugo E., Lightfoot, Ellis, Davis, Laurie S., Rothlein, Robert, Faanes, Ronald B., Lipsky, Peter E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - therapeutic use Antibody-Producing Cells - cytology Antigen-Antibody Complex - analysis Antigens - administration & dosage Antigens, CD - immunology Arthritis, Rheumatoid - etiology Arthritis, Rheumatoid - immunology Arthritis, Rheumatoid - therapy Biological and medical sciences CD18 Antigens Cell Adhesion Molecules - immunology Diseases of the osteoarticular system Inflammatory joint diseases Joints - immunology Kinetics L-Selectin Medical sciences Rabbits Synovial Membrane - cytology Synovial Membrane - pathology
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