Effects of glucose, Trolox-C, and glutathione disulphide on lipid peroxidation and cell death induced by oxidant stress in rat heart

Objective: The aim was to find effective protection of myocytes against peroxide induced damage in terms of preservation of contractile activity, protection against lipid peroxidation, and protection against cell death. Methods: The components of the glutathione redox cycle, the production of malond...

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Veröffentlicht in:	Cardiovascular research 1992-02, Vol.26 (2), p.133-142
Hauptverfasser:	Le, C T, Hollaar, L, van der Valk, E J M, van der Laarse, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - pharmacology Benzene Derivatives - pharmacology Biological and medical sciences Cardiovascular system cell death Cell Death - drug effects Cells, Cultured Chromans - pharmacology cumene hydroperoxide free radical scavengers glucose Glucose - pharmacology glutathione Glutathione - analogs & derivatives Glutathione - pharmacology Glutathione Disulfide glutathione disulphide Heart - drug effects Investigative techniques, diagnostic techniques (general aspects) lipid peroxidation Lipid Peroxidation - drug effects malondialdehyde Malondialdehyde - metabolism Medical sciences Myocardial Contraction - drug effects Myocardium - metabolism myocytes Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Rats Rats, Inbred Strains Trolox-C
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