MRI susceptometry: Image-based measurement of absolute susceptibility of MR contrast agents and human blood

We present a novel NMR imaging technique that allows absolute determination of the magnetic susceptibility constant, χ, of a solution. By comparing the phase difference of MR images produced with an instant (echo planar) “offset” spin‐echo sequence, we obtain a direct measure of the magnetic field p...

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Veröffentlicht in:Magnetic resonance in medicine 1992-04, Vol.24 (2), p.375-383
Hauptverfasser: Weisskoff, Robert M., Kiihne, Suzanne
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container_title Magnetic resonance in medicine
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creator Weisskoff, Robert M.
Kiihne, Suzanne
description We present a novel NMR imaging technique that allows absolute determination of the magnetic susceptibility constant, χ, of a solution. By comparing the phase difference of MR images produced with an instant (echo planar) “offset” spin‐echo sequence, we obtain a direct measure of the magnetic field perturbations caused by the solution. We demonstrate this method with Gd(DTPA), Dy(DTPA), human red blood cells, and superparamagnetic iron oxide particles. © 1992 Academic Press, Inc.
doi_str_mv 10.1002/mrm.1910240219
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source Wiley-Blackwell Journals; MEDLINE
subjects Biological and medical sciences
Contrast Media
Dextrans
Dysprosium
Erythrocytes
Ferrosoferric Oxide
Gadolinium
Gadolinium DTPA
Humans
Image Processing, Computer-Assisted
In Vitro Techniques
Investigative techniques, diagnostic techniques (general aspects)
Iron
Magnetic Resonance Imaging
Magnetite Nanoparticles
Medical sciences
Miscellaneous. Technology
Organometallic Compounds
Oxides
Pentetic Acid
Radiodiagnosis. Nmr imagery. Nmr spectrometry
title MRI susceptometry: Image-based measurement of absolute susceptibility of MR contrast agents and human blood
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