MRI susceptometry: Image-based measurement of absolute susceptibility of MR contrast agents and human blood
We present a novel NMR imaging technique that allows absolute determination of the magnetic susceptibility constant, χ, of a solution. By comparing the phase difference of MR images produced with an instant (echo planar) “offset” spin‐echo sequence, we obtain a direct measure of the magnetic field p...
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Veröffentlicht in: | Magnetic resonance in medicine 1992-04, Vol.24 (2), p.375-383 |
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container_title | Magnetic resonance in medicine |
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creator | Weisskoff, Robert M. Kiihne, Suzanne |
description | We present a novel NMR imaging technique that allows absolute determination of the magnetic susceptibility constant, χ, of a solution. By comparing the phase difference of MR images produced with an instant (echo planar) “offset” spin‐echo sequence, we obtain a direct measure of the magnetic field perturbations caused by the solution. We demonstrate this method with Gd(DTPA), Dy(DTPA), human red blood cells, and superparamagnetic iron oxide particles. © 1992 Academic Press, Inc. |
doi_str_mv | 10.1002/mrm.1910240219 |
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Reson. Med</addtitle><description>We present a novel NMR imaging technique that allows absolute determination of the magnetic susceptibility constant, χ, of a solution. By comparing the phase difference of MR images produced with an instant (echo planar) “offset” spin‐echo sequence, we obtain a direct measure of the magnetic field perturbations caused by the solution. We demonstrate this method with Gd(DTPA), Dy(DTPA), human red blood cells, and superparamagnetic iron oxide particles. © 1992 Academic Press, Inc.</description><subject>Biological and medical sciences</subject><subject>Contrast Media</subject><subject>Dextrans</subject><subject>Dysprosium</subject><subject>Erythrocytes</subject><subject>Ferrosoferric Oxide</subject><subject>Gadolinium</subject><subject>Gadolinium DTPA</subject><subject>Humans</subject><subject>Image Processing, Computer-Assisted</subject><subject>In Vitro Techniques</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Iron</subject><subject>Magnetic Resonance Imaging</subject><subject>Magnetite Nanoparticles</subject><subject>Medical sciences</subject><subject>Miscellaneous. Technology</subject><subject>Organometallic Compounds</subject><subject>Oxides</subject><subject>Pentetic Acid</subject><subject>Radiodiagnosis. Nmr imagery. 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Technology</topic><topic>Organometallic Compounds</topic><topic>Oxides</topic><topic>Pentetic Acid</topic><topic>Radiodiagnosis. Nmr imagery. 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Reson. Med</addtitle><date>1992-04</date><risdate>1992</risdate><volume>24</volume><issue>2</issue><spage>375</spage><epage>383</epage><pages>375-383</pages><issn>0740-3194</issn><eissn>1522-2594</eissn><coden>MRMEEN</coden><abstract>We present a novel NMR imaging technique that allows absolute determination of the magnetic susceptibility constant, χ, of a solution. By comparing the phase difference of MR images produced with an instant (echo planar) “offset” spin‐echo sequence, we obtain a direct measure of the magnetic field perturbations caused by the solution. We demonstrate this method with Gd(DTPA), Dy(DTPA), human red blood cells, and superparamagnetic iron oxide particles. © 1992 Academic Press, Inc.</abstract><cop>Baltimore</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>1569876</pmid><doi>10.1002/mrm.1910240219</doi><tpages>9</tpages></addata></record> |
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subjects | Biological and medical sciences Contrast Media Dextrans Dysprosium Erythrocytes Ferrosoferric Oxide Gadolinium Gadolinium DTPA Humans Image Processing, Computer-Assisted In Vitro Techniques Investigative techniques, diagnostic techniques (general aspects) Iron Magnetic Resonance Imaging Magnetite Nanoparticles Medical sciences Miscellaneous. Technology Organometallic Compounds Oxides Pentetic Acid Radiodiagnosis. Nmr imagery. Nmr spectrometry |
title | MRI susceptometry: Image-based measurement of absolute susceptibility of MR contrast agents and human blood |
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