Proton overhauser enhancements in human cardiac phosphorus NMR spectroscopy at 1.5 T

Narrowband irradiation of water protons with a surface coil yields significant nuclear Overhauser enhancement (nOe) of phosphocreatine (PCr) and some adenosine triphosphate (ATP) moieties in localized and unlocalized phosphorus (31P) NMR spectra from chest and heart muscle. In seven normal subjects...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Magnetic resonance in medicine 1992-04, Vol.24 (2), p.384-390
Hauptverfasser: Bottomley, Aul A., Hardy, Christopher J.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Narrowband irradiation of water protons with a surface coil yields significant nuclear Overhauser enhancement (nOe) of phosphocreatine (PCr) and some adenosine triphosphate (ATP) moieties in localized and unlocalized phosphorus (31P) NMR spectra from chest and heart muscle. In seven normal subjects at 1.5 T the nOe values were 0.6 ± 0.3, 0.6 ± 0.3, 0 ± 0.3, and 0.3 ± 0.2 for myocardial PCr, γ‐ATP, α‐ATP, and β‐ATP, respectively, not significantly different from those in chest muscle. Distortion of the measured PCr/ATP ratios due to differences in the nOe may require accurate correction to realize the full benefit of the effect in studies involving quantitative intergroup comparisons. © 1992 Academic Press, Inc.
ISSN:0740-3194
1522-2594
DOI:10.1002/mrm.1910240220