IL-28, IL-29 and their class II cytokine receptor IL-28R

Cytokines play a critical role in modulating the innate and adaptive immune systems. Here, we have identified from the human genomic sequence a family of three cytokines, designated interleukin 28A (IL-28A), IL-28B and IL-29, that are distantly related to type I interferons (IFNs) and the IL-10 fami...

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Veröffentlicht in:	Nature immunology 2003-01, Vol.4 (1), p.63-68
Hauptverfasser:	Sheppard, Paul, Kindsvogel, Wayne, Xu, Wenfeng, Henderson, Katherine, Schlutsmeyer, Stacy, Whitmore, Theodore E., Kuestner, Rolf, Garrigues, Ursula, Birks, Carl, Roraback, Jenny, Ostrander, Craig, Dong, Dennis, Shin, Jinu, Presnell, Scott, Fox, Brian, Haldeman, Betty, Cooper, Emily, Taft, David, Gilbert, Teresa, Grant, Francis J., Tackett, Monica, Krivan, William, McKnight, Gary, Clegg, Chris, Foster, Don, Klucher, Kevin M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Biomedical and Life Sciences Biomedicine Cloning, Molecular COS Cells Cytokines Gene Expression Humans Immunology In Vitro Techniques Infectious Diseases Interferons Interleukins - genetics Interleukins - metabolism Molecular Sequence Data Protein Subunits Receptors, Cytokine - chemistry Receptors, Cytokine - genetics Receptors, Cytokine - metabolism Recombinant Proteins - chemistry Recombinant Proteins - genetics Recombinant Proteins - metabolism RNA - genetics RNA - metabolism Sequence Homology, Amino Acid Signal Transduction Virus Diseases - immunology
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