Characterization of lung gamma delta T cells following intranasal infection with Mycobacterium bovis bacillus Calmette-Guérin

The lungs are considered to have an impaired capacity to contain infection by pathogenic mycobacteria, even in the presence of effective systemic immunity. In an attempt to understand the underlying cellular mechanisms, we characterized the gammadelta T cell population following intranasal infection...

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Veröffentlicht in:	The Journal of immunology (1950) 2003-01, Vol.170 (1), p.463-469
Hauptverfasser:	Dieli, Francesco, Ivanyi, Juraj, Marsh, Philip, Williams, Ann, Naylor, Irene, Sireci, Guido, Caccamo, Nadia, Di Sano, Caterina, Salerno, Alfredo
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intranasal Animals CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - microbiology CD8-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - microbiology Cell Division - immunology Cells, Cultured Cytokines - biosynthesis Cytotoxicity, Immunologic Epitopes, T-Lymphocyte - immunology Flow Cytometry Gene Rearrangement, delta-Chain T-Cell Antigen Receptor Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor Lung - cytology Lung - immunology Lung - metabolism Lymphocyte Activation Lymphocyte Depletion Mice Mice, Inbred C57BL Mycobacterium bovis - immunology Receptors, Antigen, T-Cell, gamma-delta - analysis Receptors, Antigen, T-Cell, gamma-delta - biosynthesis Receptors, Antigen, T-Cell, gamma-delta - genetics T-Lymphocyte Subsets - cytology T-Lymphocyte Subsets - immunology T-Lymphocyte Subsets - metabolism T-Lymphocyte Subsets - microbiology T-Lymphocytes, Cytotoxic - immunology T-Lymphocytes, Cytotoxic - metabolism T-Lymphocytes, Cytotoxic - microbiology Tuberculosis - immunology Tuberculosis - microbiology
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