eMelanoBase: An online locus-specific variant database for familial melanoma

A proportion of melanoma‐prone individuals in both familial and non‐familial contexts has been shown to carry inactivating mutations in either CDKN2A or, rarely, CDK4. CDKN2A is a complex locus that encodes two unrelated proteins from alternately spliced transcripts that are read in different frames...

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Veröffentlicht in:	Human mutation 2003-01, Vol.21 (1), p.2-7
Hauptverfasser:	Fung, David C.Y., Holland, Elizabeth A., Becker, Therese M., Hayward, Nicholas K., Paillerets, Brigitte Bressac-de, Consortium, Melanoma Genetics, Mann, Graham J.
Format:	Artikel
Sprache:	eng
Schlagworte:	CDK4 CDKN2A Computer Security Cyclin-Dependent Kinase 4 Cyclin-Dependent Kinases - genetics Databases, Nucleic Acid - standards familial Forecasting Genes, p16 Genetic Predisposition to Disease Genotype Germ-Line Mutation germline variants Humans Information Storage and Retrieval Internet melanoma Melanoma - genetics melanoma, familial model-view-controller architecture Molecular Sequence Data Mutation Proto-Oncogene Proteins Quality Control Software Terminology as Topic
Online-Zugang:	Volltext
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