Interaction of glucocorticoid analogues with the human glucocorticoid receptor

Transient co-transfection of receptor cDNA and suitable reporter genes was used to study human glucocorticoid receptor (hGR) function in a neutral mammalian cell background. A variety of natural and synthetic steroids were analyzed for their ability to activate gene expression through the hGR and to...

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Veröffentlicht in:	The Journal of steroid biochemistry and molecular biology 1992-03, Vol.41 (3), p.733-738
Hauptverfasser:	Berger, Tina S., Parandoosh, Zahra, Perry, Bruce W., Stein, Robert B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding, Competitive Cell Line DNA - genetics Gene Expression Regulation - drug effects Glucocorticoids - pharmacology Humans Receptors, Glucocorticoid - drug effects Receptors, Glucocorticoid - genetics Receptors, Glucocorticoid - metabolism Structure-Activity Relationship Transcriptional Activation Transfection
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