Induction of neural differentiation by electrically stimulated gene expression of NeuroD2

Regulation of cell differentiation is an important assignment for cellular engineering. One of the techniques for regulation is gene transfection into undifferentiated cells. Transient expression of NeuroD2, one of neural bHLH transcription factors, converted mouse N1E-115 neuroblastoma cells into d...

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Veröffentlicht in:	Journal of biotechnology 2003-02, Vol.100 (3), p.231-238
Hauptverfasser:	Mie, Masayasu, Endoh, Tamaki, Yanagida, Yasuko, Kobatake, Eiry, Aizawa, Masuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basic Helix-Loop-Helix Transcription Factors Biological and medical sciences Cell Differentiation - genetics Cell Differentiation - radiation effects Cell Line Cloning, Molecular Electric Stimulation Electrical stimulation Electromagnetic Fields Fundamental and applied biological sciences. Psychology Gene Expression Regulation - radiation effects Heat shock protein promoter HSP70 Heat-Shock Proteins - metabolism HSP70 Heat-Shock Proteins - radiation effects Mice Neural differentiation Neuroblastoma - pathology Neuroblastoma - physiopathology NeuroD2 Neuropeptides - biosynthesis Neuropeptides - genetics Transcription Factors - biosynthesis Transcription Factors - genetics Transfection - methods
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