Isolation and characterization of the human sucrase-isomaltase gene and demonstration of intestine-specific transcriptional elements

The molecular mechanisms that regulate intestine-specific gene expression and the transition from proliferating, undifferentiated crypt cells to nonproliferating, differentiated villus cells are unknown. Sucrase-isomaltase is an apical membrane disaccharidase that is found exclusively in enterocytes...

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Veröffentlicht in:	The Journal of biological chemistry 1992-04, Vol.267 (11), p.7863-7870
Hauptverfasser:	Wu, G D, Wang, W, Traber, P G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - metabolism Base Sequence Cell Line Chloramphenicol O-Acetyltransferase - metabolism Cloning, Molecular Colonic Neoplasms - metabolism DNA Gene Expression Regulation, Enzymologic genes HeLa Cells Humans Intestine, Small - metabolism Luciferases - genetics Molecular Sequence Data Polymerase Chain Reaction promoters Regulatory Sequences, Nucleic Acid Restriction Mapping Sucrase-Isomaltase Complex - genetics Transcription, Genetic Transfection Tumor Cells, Cultured
Online-Zugang:	Volltext
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