Characterization of the cell death modes and the associated changes in cellular energy supply in response to AlPcS4-PDT

Photodynamic therapy (PDT) can result in both types of cell death, apoptosis or necrosis. Several steps in the induction and execution of apoptosis depend on ATP and the intracellular ATP level has been shown to be one determinant in whether apoptosis or necrosis occurs. Therefore, photochemical dam...

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Veröffentlicht in:	Photochemical & photobiological sciences 2002-03, Vol.1 (3), p.172-177
Hauptverfasser:	Plaetzer, Kristjan, Kiesslich, Tobias, Krammer, Barbara, Hammerl, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Caspases - metabolism Cell Death - drug effects Enzyme Induction Humans Indoles - pharmacology Mitochondria - drug effects Mitochondria - enzymology Organometallic Compounds - pharmacology Photochemotherapy Photosensitizing Agents - pharmacology Tumor Cells, Cultured
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