Effect of different dose schedules of bimatoprost on intraocular pressure and pupil size in the glaucomatous beagle

The changes in intraocular pressure and pupil size in glaucomatous dogs were evaluated after instillations of 0.03% bimatoprost (Lumigan, Allergan, Irvine, CA USA) once in the morning, or once in the evening, or twice daily in five day multiple dose studies. Applanation tonometry (IOP) and pupil siz...

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Veröffentlicht in:	Journal of ocular pharmacology and therapeutics 2002-12, Vol.18 (6), p.525-534
Hauptverfasser:	GELATT, Kirk N, MACKAY, Edward O
Format:	Artikel
Sprache:	eng
Schlagworte:	Amides Animals Bimatoprost Biological and medical sciences Cloprostenol - analogs & derivatives Dogs Drug Administration Schedule Eye Female Glaucoma - drug therapy Glaucoma - physiopathology Intraocular Pressure - drug effects Lipids - administration & dosage Male Medical sciences Methylcellulose - administration & dosage Ophthalmic Solutions - administration & dosage Pharmacology. Drug treatments Placebos - administration & dosage Pupil - drug effects
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