Closed loops: persistence of the protein chain returns

It has recently been discovered that globular proteins are universally built from standard loop-n-lock units of about 30 amino acid residues. The hypothesis has been put forward on the loop stage in the protein evolution when the units were autonomous. Later they joined together making longer chains...

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Veröffentlicht in:	Protein engineering 2002-12, Vol.15 (12), p.955-957
Hauptverfasser:	Berezovsky, Igor N., Kirzhner, Valery M., Kirzhner, Alla, Rosenfeld, Vladimir R., Trifonov, Edward N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Motifs Amino Acid Sequence closed loops Conserved Sequence Databases, Protein Evolution, Molecular Models, Molecular protein chain return persistence Protein Conformation protein evolution Protein Folding Proteins - chemistry Structural Homology, Protein
Online-Zugang:	Volltext
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