Reassessment of the resistance of Plasmodium falciparum to chloroquine in Gabon: implications for the validity of tests in vitro vs. in vivo

Increasing resistance of Plasmodium falciparum to antimalarial drugs presents a major risk factor for people living in endemic areas of tropical Africa. In Lambaréné, Gabon, regular surveillance of chloroquine sensitivity of P. falciparum in vitro has been carried out since 1992 using the WHO standa...

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Veröffentlicht in:	Transactions of the Royal Society of Tropical Medicine and Hygiene 2002-11, Vol.96 (6), p.660-663
Hauptverfasser:	Borrmann, S., Binder, R.K., Adegnika, A.A., Missinou, M.A., Issifou, S., Ramharter, M., Wernsdorfer, W.H., Kremsner, P.G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antimalarials - therapeutic use Antiparasitic agents Biological and medical sciences Child Child, Preschool Chloroquine - therapeutic use chloroquine resistance Drug Resistance Gabon Human protozoal diseases Humans Infectious diseases Malaria Malaria, Falciparum - drug therapy Medical sciences Parasitic diseases Pharmacology. Drug treatments Plasmodium falciparum Plasmodium falciparum - drug effects Protozoal diseases Risk Factors test in vitro test in vivo Tropical medicine WHO microtest
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