Monoclonal antibodies affecting sperm-zona binding and/or zona-induced acrosome reaction

The majority of anti-sperm monoclonal antibodies which were shown to inhibit in vitro fertilization in our laboratory react with antigens in the acrosomal region of spermatozoa. To elucidate the mechanism of human and/or mouse fertilization inhibition, the effects of these antibodies on mouse sperm-...

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Veröffentlicht in:	Journal of reproductive immunology 1992-03, Vol.21 (2), p.175-187
Hauptverfasser:	Fann, Chorng-Hwa, Lee, Chi-Yu Gregory
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrosome - physiology Animals anti-sperm monoclonal antibodies Antibodies, Monoclonal - immunology Biological and medical sciences Birth control Female Fertilization in Vitro Fluorescent Antibody Technique Gynecology. Andrology. Obstetrics Humans in vitro fertilization Male Medical sciences Mice Mice, Inbred Strains Sperm-Ovum Interactions - immunology sperm-zona binding Spermatozoa - immunology Spermatozoa - physiology Sterility. Assisted procreation Zona Pellucida - physiology zona-induced acrosome reaction
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