Can prevention trials test theories of etiology?
This paper addresses the issue of whether prevention research methods, particularly those involving randomized prevention trials, can be used to test theories concerning the etiology of psychopathology. Based on recent empirical and theoretical work in developmental psychopathology, three aspects of...
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| Veröffentlicht in: | Development and psychopathology 2002-12, Vol.14 (4), p.673-694 |
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| container_title | Development and psychopathology |
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| creator | HOWE, GEORGE W. REISS, DAVID YUH, JONGIL |
| description | This paper addresses the issue of whether prevention research methods, particularly those involving randomized prevention trials, can be used to test theories concerning the etiology of psychopathology. Based on recent empirical and theoretical work in developmental psychopathology, three aspects of etiologic theory are discussed: risk and protective mechanisms, the integration of environmental and genetic factors, and patterns of developmental progression in psychopathology across the life span. It is suggested that integration of prevention trial methods with methods from passive correlational designs, behavioral genetics, and longitudinal studies allows for unique opportunities to test hypotheses about etiology. Empirical literature on the development and prevention of internalizing disorders, particularly depression, is presented to support this argument. Limitations of prevention trials for testing theory are also reviewed. |
| doi_str_mv | 10.1017/S0954579402004029 |
| format | Article |
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Based on recent empirical and theoretical work in developmental psychopathology, three aspects of etiologic theory are discussed: risk and protective mechanisms, the integration of environmental and genetic factors, and patterns of developmental progression in psychopathology across the life span. It is suggested that integration of prevention trial methods with methods from passive correlational designs, behavioral genetics, and longitudinal studies allows for unique opportunities to test hypotheses about etiology. Empirical literature on the development and prevention of internalizing disorders, particularly depression, is presented to support this argument. 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Limitations of prevention trials for testing theory are also reviewed.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Depressive Disorder, Major - etiology</subject><subject>Depressive Disorder, Major - prevention & control</subject><subject>Design</subject><subject>Etiology</subject><subject>Humans</subject><subject>Hypotheses</subject><subject>Intervention</subject><subject>Longitudinal studies</subject><subject>Mental depression</subject><subject>Prevention programs</subject><subject>Psychological Theory</subject><subject>Psychology, Child</subject><subject>Psychopathology</subject><subject>Randomized Controlled Trials as Topic</subject><subject>Research methodology</subject><subject>Risk factors</subject><subject>Young adults</subject><issn>0954-5794</issn><issn>1469-2198</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kE1Lw0AQhhdRtH78AC8SPHiLzmz2I3sSKVrFgop6XjbJRKNtUndT0X_vlhYFxcvM4X1meHgZ20c4RkB9cg9GCqmNAA4Qh1ljAxTKpBxNvs4Gizhd5FtsO4QXAJCZkJtsC7kURhkzYDB0bTLz9E5t33Rt0vvGTULSU-iT_pk631BIujqhmE66p8_TXbZRR4L2VnuHPV6cPwwv0_HN6Gp4Nk6d4LpPnULUlauVRKRKKF5iVkBRayd1XRqSZS20A-7KQtYlYWFQkeCVgByKnHi2w46Wf2e-e5tHHTttQkmTiWupmwereZ4ZECKCh7_Al27u2-hmOaAyQuYYIVxCpe9C8FTbmW-mzn9aBLvo0v7pMt4crB7PiylVPxer8iKQLoEm9PTxnTv_apXOtLRqdGdzI0aYjW_tdeSzlYSbFr6pnuhH9X-NL8gCi6s</recordid><startdate>20021201</startdate><enddate>20021201</enddate><creator>HOWE, GEORGE W.</creator><creator>REISS, DAVID</creator><creator>YUH, JONGIL</creator><general>Cambridge University Press</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>K7.</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>20021201</creationdate><title>Can prevention trials test theories of etiology?</title><author>HOWE, GEORGE W. ; REISS, DAVID ; YUH, JONGIL</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a427t-a6117daf6511ed462c13b0bf7a57fc9e5cf47a02acb5fce1b916e42d4080b8e23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Depressive Disorder, Major - etiology</topic><topic>Depressive Disorder, Major - prevention & control</topic><topic>Design</topic><topic>Etiology</topic><topic>Humans</topic><topic>Hypotheses</topic><topic>Intervention</topic><topic>Longitudinal studies</topic><topic>Mental depression</topic><topic>Prevention programs</topic><topic>Psychological Theory</topic><topic>Psychology, Child</topic><topic>Psychopathology</topic><topic>Randomized Controlled Trials as Topic</topic><topic>Research methodology</topic><topic>Risk factors</topic><topic>Young adults</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>HOWE, GEORGE W.</creatorcontrib><creatorcontrib>REISS, DAVID</creatorcontrib><creatorcontrib>YUH, JONGIL</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Criminal Justice (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Development and psychopathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>HOWE, GEORGE W.</au><au>REISS, DAVID</au><au>YUH, JONGIL</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Can prevention trials test theories of etiology?</atitle><jtitle>Development and psychopathology</jtitle><addtitle>Dev Psychopathol</addtitle><date>2002-12-01</date><risdate>2002</risdate><volume>14</volume><issue>4</issue><spage>673</spage><epage>694</epage><pages>673-694</pages><issn>0954-5794</issn><eissn>1469-2198</eissn><abstract>This paper addresses the issue of whether prevention research methods, particularly those involving randomized prevention trials, can be used to test theories concerning the etiology of psychopathology. 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| ispartof | Development and psychopathology, 2002-12, Vol.14 (4), p.673-694 |
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| source | MEDLINE; Cambridge University Press Journals Complete |
| subjects | Adolescent Adult Depressive Disorder, Major - etiology Depressive Disorder, Major - prevention & control Design Etiology Humans Hypotheses Intervention Longitudinal studies Mental depression Prevention programs Psychological Theory Psychology, Child Psychopathology Randomized Controlled Trials as Topic Research methodology Risk factors Young adults |
| title | Can prevention trials test theories of etiology? |
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