LEUKAEMIA INHIBITORY FACTOR (LIF) IS EXPRESSED IN HYPERTROPHIC CHONDROCYTES AND VASCULAR SPROUTS DURING OSTEOGENESIS

Avascular cartilage is replaced by highly vascularized bone tissue during endochondral ossification, a process involving capillary invasion of calcified hypertrophic cartilage in association with apoptosis of hypertrophic chondrocytes, degradation of cartilage matrix and deposition of bone matrix. A...

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Veröffentlicht in:	Cytokine (Philadelphia, Pa.) Pa.), 2002-12, Vol.20 (5), p.224-230
Hauptverfasser:	Grimaud, E, Blanchard, F, Charrier, C, Gouin, F, Redini, F, Heymann, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cartilage, Articular - growth & development Cartilage, Articular - metabolism Chondrocytes - metabolism Embryonic and Fetal Development - physiology Growth Inhibitors - biosynthesis Growth Inhibitors - genetics Humans Immunohistochemistry Interleukin-6 Leukemia Inhibitory Factor LIF/osteogenesis/chondrocytes/calcified cartilage/bone metabolism Lymphokines - biosynthesis Lymphokines - genetics Osteogenesis - physiology Rats Rats, Sprague-Dawley
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