Differential regulation of chromogranin B/secretogranin I and secretogranin II by forskolin in PC12 cells

The factors which regulate the expression of the granin family of secretory proteins have yet to be completely described. The present study investigated the effects of forskolin (FSK), an activator of adenylate cyclase, on the regulation of chromogranin B/secretogranin I (CgB) and secretogranin II (...

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Veröffentlicht in:	Brain research. Molecular brain research. 1992, Vol.12 (1), p.195-202
Hauptverfasser:	Thompson, Marilyn E., Zimmer, Warren E., Wear, Laurie B., MacMillan, Lee Ann, Thompson, W.Joseph, Huttner, Wieland B., Hidaka, Hiroyoshi, Scammell, Jonathan G.
Format:	Artikel
Sprache:	eng
Schlagworte:	8-Bromo-cAMP Amino Acid Isomerases - genetics Amino Acid Isomerases - metabolism Animals Biological and medical sciences Blotting, Northern Carrier Proteins - genetics Carrier Proteins - metabolism Chromogranin B Chromogranins Colforsin - pharmacology cyclic AMP Cyclic AMP - metabolism DNA Probes Fundamental and applied biological sciences. Psychology Gene Expression - drug effects Genic rearrangement. Recombination. Transposable element Granin Immunofluorescence Immunohistochemistry Molecular and cellular biology Molecular genetics Northern blot PC12 Cells Peptidylprolyl Isomerase Potassium Chloride - pharmacology Proteins - analysis Proteins - genetics Proteins - metabolism Regulated secretion RNA, Messenger - genetics RNA, Messenger - isolation & purification RNA, Messenger - metabolism Western blot
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