Effect of Topical Retinoic Acids on the Levels of Collagen mRNA During the Repair of UVB-Induced Dermal Damage in the Hairless Mouse and the Possible Role of TGF-β as a Mediator

Topically applied retinoic acids have been found to enhance the gene expression for collagen types I and III in the skin of UVB irradiated hairless mice. Prior damage is required because the effect is not observed in the skin of age matched, non irradiated control animals. Immunochemical methods hav...

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