PARK6 is a common cause of familial parkinsonism

The Parkin gene is responsible for about 50% of autosomal recessive juvenile parkinsonism (ARJP) and less than 20% of sporadic early onset cases. We recently mapped a novel ARJP locus (PARK6) on chromosome 1p. Linkage to PARK6 was confirmed in 8 families from 4 different European countries. These fa...

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Veröffentlicht in:	Neurological sciences 2002-09, Vol.23 Suppl 2, p.S117-s118
Hauptverfasser:	Valente, E M, Brancati, F, Caputo, V, Graham, E A, Davis, M B, Ferraris, A, Breteler, M M B, Gasser, T, Bonifati, V, Bentivoglio, A R, De Michele, G, Dürr, A, Cortelli, P, Filla, A, Meco, G, Oostra, B A, Brice, A, Albanese, A, Dallapiccola, B, Wood, N W
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromosomes, Human, Pair 1 Europe - epidemiology Genetic Linkage Genotype Humans Ligases - genetics Neurology Neurosciences Parkinsonian Disorders - epidemiology Parkinsonian Disorders - genetics Pedigree Ubiquitin-Protein Ligases
Online-Zugang:	Volltext
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