Increased S100β neurotrophic activity in Alzheimer's disease temporal lobe

The confirming diagnosis of Alzheimer's disease includes an assessment of the concentration of neuritic plaques in the temporal lobe of the brain. The presence of abnormal levels of neurotrophic factors in Alzheimer's disease is one possible explanation for the increased concentration of a...

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Veröffentlicht in:	Neurobiology of aging 1992, Vol.13 (1), p.1-7
Hauptverfasser:	Marshak, Daniel R., Pesce, Susan Ann, Stanley, Laura C., Griffin, W.Sue T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Aging Alzheimer Disease - metabolism Alzheimer Disease - pathology Alzheimer's disease Astrocytes Autoradiography Biological and medical sciences Cloning, Molecular Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Female Gliosis Gliosis - pathology Humans Immunoblotting Immunohistochemistry Male Medical sciences Middle Aged Neurites - drug effects Neurites - metabolism Neuritic plaques Neurology Neurotrophic factors Radioimmunoassay RNA - metabolism S100 Proteins - metabolism S100β Temporal lobe Temporal Lobe - metabolism Tissue Fixation
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