Role of the Autoimmune Regulator (AIRE) gene in alopecia areata: Strong association of a potentially functional AIRE polymorphism with alopecia universalis

: Alopecia areata is characterized by a reversible form of patchy or complete hair loss associated with T‐cell infiltration of hair follicles. The lifetime disease risk of ∼1.4% in the general population is increased to more than 30% in autoimmune polyendocrinopathy candidiasis ectodermal dysplasia...

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Veröffentlicht in:	Tissue antigens 2002-12, Vol.60 (6), p.489-495
Hauptverfasser:	Tazi-Ahnini, R., Cork, M.J., Gawkrodger, D.J., Birch, M.P., Wengraf, D., McDonagh, A.J.G., Messenger, A.G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over AIRE Protein alopecia areata Alopecia Areata - genetics Alopecia Areata - immunology autoimmune polyendocrinopathy candidiasis ectodermal dysplasia syndrome autoimmune regulator gene Case-Control Studies Child Down's syndrome Female Genotype Humans major histocompatibility complex Male Middle Aged Polyendocrinopathies, Autoimmune - genetics Polyendocrinopathies, Autoimmune - immunology Polymorphism, Restriction Fragment Length Transcription Factors - genetics Transcription Factors - immunology White People - genetics
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