H‐2‐linked control of the Yaa gene‐induced acceleration of lupus‐like autoimmune disease in BXSB mice

The accelerated development of lupus‐like autoimmune disease in male BXSB mice (H‐2b, I‐E−) is associated to the presence of a mutant gene, designated Yaa, located on their Ychromosome. To investigate whether the H‐2b haplotype and/or the lack of expression of I‐E molecules play any role in the Yaa‐...

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