Fumaric acid esters are potent immunosuppressants: inhibition of acute and chronic rejection in rat kidney transplantation models by methyl hydrogen fumarate

The effectiveness and safety of fumaric acid esters (FAEs) for the treatment of psoriasis has been demonstrated. Their mode of action, however, is poorly understood. To determine the immunomodulatory potential of calcium methyl hydrogen fumarate (CaMHF) in transplant models, we tested the compound i...

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Veröffentlicht in:	Archives of Dermatological Research 2002-12, Vol.294 (9), p.399-404
Hauptverfasser:	LEHMANN, Manfred, RISCH, Kirsten, NIZZE, Horst, LUTZ, Jens, HEEMANN, Uwe, VOLK, Hans-Dieter, ASADULLAH, Khusru
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Animals Biological and medical sciences Chronic Disease Creatinine - blood Fumarates - therapeutic use Graft Rejection - drug therapy Graft Rejection - prevention & control Graft Survival - drug effects Immunosuppressive Agents - therapeutic use Kidney Transplantation Male Medical sciences Pharmacology. Drug treatments Rats Rats, Inbred Strains Skin, nail, hair, dermoskeleton
Online-Zugang:	Volltext
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