Binding of basic peptides to acidic lipids in membranes: effects of inserting alanine(s) between the basic residues

We studied the binding of peptides containing five basic residues to membranes containing acidic lipids. The peptides have five arginine or lysine residues and zero, one, or two alanines between the basic groups. The vesicles were formed from mixtures of a zwitterionic lipid, phosphatidylcholine, an...

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