Cystatins and stefins in ascites fluid from ovarian carcinoma

Cysteine proteinase inhibitors (CpI) of all three families were found in ascites fluid from patients with ovarian carcinoma. CPIs were isolated by affinity chromatography on carboxymethylated papain Sepharose, followed by gel filtration, anti-stefin-Sepharose and ion exchange chromatography. The hig...

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Veröffentlicht in:	Cancer letters 1992-01, Vol.61 (3), p.243-253
Hauptverfasser:	Lah, T.T., Kokalj-Kunovar, M., Kastelic, L., Babnik, J., Štolfa, A., Rainer, S., Turk, V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged ascites fluid Ascitic Fluid - chemistry Ascitic Fluid - enzymology Biological and medical sciences cathepsin B Cathepsin B - antagonists & inhibitors Cathepsin B - metabolism Chromatography, Affinity Cystatin B cystatins Cystatins - isolation & purification Cystatins - metabolism Electrophoresis, Polyacrylamide Gel Female Female genital diseases Gynecology. Andrology. Obstetrics Humans Kinetics Medical sciences Middle Aged Molecular Weight ovarian cancer Ovarian Neoplasms - chemistry Ovarian Neoplasms - enzymology proteinase inhibitors stefins Tumors
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