Decreases in unintegrated HIV DNA are associated with antiretroviral therapy in AIDS patients

Better markers are needed to monitor the efficacy of antiretroviral drugs in persons infected with human immunodeficiency virus (HIV). We investigated the effects of zidovudine (ZDV) and dideoxycytidine (ddC) on the presence of unintegrated HIV-1 DNA in peripheral blood mononuclear cells (PBMCs) fro...

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Veröffentlicht in:	Journal of acquired immune deficiency syndromes (1988) 1992, Vol.5 (1), p.31-36
Hauptverfasser:	DICKOVER, R. E, DONOVAN, R. M, GOLDSTEIN, E, COHEN, S. H, BOLTON, V, HUTH, R. G, LIU, G, CARLSON, J. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired Immunodeficiency Syndrome - drug therapy Acquired Immunodeficiency Syndrome - microbiology AIDS/HIV Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Biological and medical sciences DNA, Viral - blood DNA, Viral - chemistry DNA, Viral - genetics Drug Resistance, Microbial HIV-1 - drug effects HIV-1 - genetics Humans Leukocytes, Mononuclear - microbiology Medical sciences Molecular Weight Pharmacology. Drug treatments Polymerase Chain Reaction Virus Integration Zalcitabine - pharmacology Zalcitabine - therapeutic use Zidovudine - pharmacology Zidovudine - therapeutic use
Online-Zugang:	Volltext
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